Dog dizzy on Zonisamide for seizures. Can I safely reduce her dose?

Question

I have an 8 year old chesapeake who is epileptic. She is taking 100 mg Zonisamide tablets (2 tablets twice a day), and Potassium Bromide solution (4.5 cc/ night). I can't reduce her potassium bromide dosage because she will seizure. I was wondering if I could reduce the Zonisamide dosage. She has been extra dizzy lately, and I know that is one of the main side effects of Zonisamide. Any help would be greatly appreciated. Thanks. Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 8 years and 5 months old | 60 lbs

Ann Dion, DVM · Accepted Answer

Hello. I am sorry that Bayleigh isn't feeling well. Decreasing any seizure medication can result in a seizure, and is never recommended without direct veterinary supervision. If you feel that the Zonisamide is resulting in negative side effects, chat with your vet about switching to either Pexion or Phenobarbital or Keppra. These are newer medications that may have less side effects for Bayleigh. Depending on her levels and the medications, your vet will tell you how to switch safely. Good luck with her!

Dog dizzy on Zonisamide for seizures. Can I safely reduce her dose?

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