Petco Text Logo
Petco Pet Logo

My senior dog has high liver enzymes. What's the cause and next steps?

Updated On September 23rd, 2025

What could cause a senior dogg's liver enzymes to be high? Her bile test was normal, her liver did look enlarged a little. She also pants more and sometimes there is a high pitch that comes out of her nose when sleeping.

1 Answer

Most Helpful Answer

Image profile

Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on August 2nd, 2018

Thanks for using Petco Pet Education Center, formerly Petcoach! Liver enzymes can be elevated for a variety of reasons and thankfully, it is not always something severe or that needs treatment. This of course depends on many factors that I do not know at this moment such as which specific enzymes are elevated. However, normal bile acids test indicate normal liver function which is good. Some of the things that can cause liver enzyme elevation include hepatitis, cholangiohepatitis, Cushing's disease, among many other possibilities. Further diagnostics will depend on the specific pattern of liver enzyme elevation but can include abdominal ultrasound, a blood test for Cushing's disease, among other diagnostics. I recommend that you have her evaluated by your veterinarian for further investigation of these changes. I hope that this is nothing concerning. Good luck!

Vote icon

1Pet Parents found this answer helpful

image
Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Sponsored