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Cat epilepsy: Meds not working for long seizures. What can I do?

Updated On September 23rd, 2025

Pet's info: Cat | Siamese | Male | neutered | 2 years and 4 months old | 11 lbs

I have a cat about 2 years old and he's been having seizures about weekly. We've done all sort of tests and exams including a CAT scan and the vet says he has epilepsy. He takes phenobarbital, diazepam and he started potassium bromide 3 months ago. He spent 1 month and 5 days without a seizure but then he had one over an hour whereas all of the previous ones were under 1 to 2 minutes. He doesn't purr and he's always itching. I've been to 3 vets and they all say the same. What else can I do?

1 Answer

Most Helpful Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on November 3rd, 2017

Thanks for using Petco Pet Education Center, formerly Petcoach! Sorry that you are going through this. Good job, it sounds like you have done everything you can to help Texugo. A seizure that long would be very concerning if he truly was having seizures that whole time. There are other medications you can add on to the ones that you are giving at this moment. Generally diazepam is avoided in cats as it can affect the liver. I think that you could consider adding a medication called zonisamide to the phenobarbital and potassium bromide. You could discuss this with your veterinarian to see if that would be ok based on his current condition but that may help control the seizures. Good luck!

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