Petco Text Logo
Petco Pet Logo

Puppy itching after NexGard. Is this normal or should I switch brands?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Male | neutered | 4 months and 7 days old | 18 lbs

NexGard seems to make our puppy itch. We have only had him 2 weeks, he does not have fleas. We gave him his monthly pill as instructed by the Vet and he is itching now. Is that ok or should we switch brands for next month? 18 pound spaniel-terrier mix. About 4 months old.

1 Answer

Most Helpful Answer

Image profile

Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on May 7th, 2018

Thanks for using Petco Pet Education Center, formerly Petcoach! I would not recommend that you switch him yet as this may be completely coincidental. Nexgard is a great preventative and I would give it more time before switching to something else. Hopefully the scratching is not a reaction to it as that would be quite unusual. If the itchiness continues despite giving it a few days, that would likely be due to allergies rather than a cause of using Nexgard. It really comes down to figuring out what is causing his allergies so that they can be treated or the specific allergen avoided. A secondary infection is likely and also needs to be addressed. There are many things that can cause allergies though in most cases they can be broken down into 3 big categories: flea, food and environmental allergies. Allergies are usually worked up in a stepwise fashion starting with flea allergies as this is the easiest and cheapest to take care of. If not on a flea preventative, then it would be a good idea to get started on one. If already on one then it would be a good idea to change to something else (there are many new products out in the market). If not improved in 1-3 months then it is time to move on and check for food allergies by switching to a novel diet (new protein and new carbohydrate). If that does not seem to be the issue then you are left out having to check for environmental allergies which require blood and/or skin tests. Allergies can be very frustrating to deal with at first but so rewarding at the end when we are able to treat them effectively!

Vote icon

5Pet Parents found this answer helpful

image
Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Sponsored