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My puppy has high ALP levels. Is this normal for a growing dog?

Updated On September 23rd, 2025

Pet's info: Dog | Golden Retriever | Female | unspayed | 8 months and 20 days old | 45 lbs

Luna's Alkaline Phosphatase levels are 350 (normal range is 3-73). The vet has suggested a low carb diet and prescribed Demanarin capsules and Vitamin B supplements. What could be the reason of the elevation?

2 Answers

Most Helpful Answer

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Answered By Makenzie Kurth, DVM

Veterinarian

Published on October 27th, 2018

She is a puppy. An elevated ALP is normal in puppies. ALP can go up because of liver problems, but also increases during bone growth. I see this elevation in about 80% of puppy bloodwork. I do not treat this as it it is not a problem and the value becomes normal when they stop growing. If there are other liver values elevated, then I am concerned, but ALP alone is not generally a problem. Per IDEXX, one of the largest veterinary pathology services in the United States, ALP values in puppies can be elevated 4 times normal (which is about where Luna is.) Denamarin, Vitamin B, and a low-carb diet will not hurt Luna, but they probably won’t change the ALP either. Best wishes to you and Luna.

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    Answered By Daniel Fonza, DVM

    Veterinarian

    Published on October 30th, 2017

    Hi there and thank you for using Pet Coach to address your concern. The ALP being elevated in a young puppy like this is normal and to be expected. Growing puppies will typically have an elevated level due to bone growth. This is nothing to be concerned about. I would follow the recommendations for treating the symptoms as your vet should have recommended. If you have any other questions or concerns, please do not hesitate to contact me. I am also available via consultation if needed.

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