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My dog's blood test shows high AlkP and lipase. Should I worry?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 10 years and 8 months old | 65 lbs

Phil hadbloodwork and had high AlkP 285 and lipase 2542 . MCV was just a little high and MCHC was a little low also. He had not eaten breakfast , only had two treats the tech gave him . I’m wondering how serious these levels are and what could cause them to be high , possible treatments . He went in for a lump check on chest, they said it’s most likely a small lipoma and isn’t growing fast since last check and recommended not having it removed due to his age and stressing him out. vacs current

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1 Answer

Most Helpful Answer

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Answered By Jeffrey Milner

Veterinarian

Published on November 6th, 2017

The blood work changes you are seeing are not very significant in the absence of any pertinent clinical signs. Increased lipase can be associated with pancreatitis, but usually a follow up blood test would only be done if there was evidence of this condition in Phil's overall health and well being (lethargy, vomiting, pain in the abdomen). MCV / MCHC changes are insigificant in the absence of a concurrent anemia. The alkaline phos change is very small. I would continue to monitor Phil's blood work on a twice yearly basis for the time being unless there are significant changes to his health where it would be warranted more frequently. Hope this helps.

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