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Cat drooling and foaming after Advantage flea spray. Is it toxic?

Updated On September 23rd, 2025

i recently (yesterday)put advantage fleas and ticks(spray) on one of my cats and she doesn't have a reaction to it... im just concerned about her grooming because everytime she does she starts to drool and her mouth foams for 5 mins and stop .... should i was her with dawn to ease the treatment so she can groom with out drooling or should i be worried?

2 Answers

Most Helpful Answer

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Answered By Sara Farmer, DVM

Veterinarian

Published on November 8th, 2019

Advantage spray shouldn’t be toxic if a typical dose was ingested by your cat but it does sound like she doesn’t like the taste. It might be best to wash the product off with dish soap, but she’ll need another product for flea prevention. You could ask your vet for a prescription topical, or something like Frontline (fipronil only) would be safe to use after the Advantage spray. Be sure to apply it to the back of her neck where she can’t groom.

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Other Answers

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    Answered By Allison Newth, VMD

    Veterinarian

    Published on July 20th, 2017

    Cats can be extremely sensitive to medications whether they be given by mouth or applied to the skin and coat. Often when a cat gets something irritating in their mouth they respond by forming foam from their saliva. I would contact your groomer and find out the exact product they used on Alpha (including the active ingredient) and contact either your veterinarian or animal poison control (https://www.aspca.org/pet-care/animal-poison-control) to find out whether the active ingredient could be causing this reaction. I would also recommend rinsing him off in case there is any remaining product on his fur that he might be able to lick off. Flea product toxicity can be very serious in any animal but cats seem to be particularly affected so do not hesitate to bring Alpha to your vet to be examined. They may recommend some bloodwork to make sure there hasn't been any internal organ or electrolyte abnormalities from whatever he may have ingested. I hope this helps.

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