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My cat has Mycoplasma, needs transfusion. What's the prognosis?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Mediumhair | Male | neutered | 2 years and 4 months old | 7.3 lbs

Our cat has been prov. diagnosed with Mycoplasma. Prescribed Ronaxan & Prednicare. Symptoms: sneezing, lack of appetite. Weight dropped from 4kg 6 mths ago to 3.2kg. Blood test (att) reveals low count, requiring transfusion. Cat is likely cat flu career (from birth), & suffers regular cat colds. We gather Mycoplasma never goes away & in cats with other conditions, prognosis generally not great / likely to reoccur. Looking for realistic / pragmatic prognosis / 2nd opinion please. Thanks

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Answered By Dr Stafford, BVetMed, MRCVS

Veterinarian

Published on May 10th, 2018

Anaemia caused by Mycoplasma can be very serious as I know you are well aware. Anaemia can be caused by a number if different diseases and the best way to confirm mycoplasmosis tends to be on a pcr test. Although it can be diagnosed on culture of bodily fluids. Mycoplasma are hardy bacteria and require a long course if strong antibiotics to cure. An otherwise healthy cat on a long course of the appropriate antibiotic would be expected to have a good chance of making a full recovery. However a cat with an already compromised immune system will not have such good chances. Having said that diseases such as FIV and Felv and FIP would be most concerning for the immune system. You could consider having your cat screened for these conditions as he may have an underlying issue. If so then prognosis is poor. However, if this is not the case and he is well enough to be treated from home It won't do any harm to give the medication a week or 2 and see how he fares. If he does get over the infection you can help prevent reinvention by keeping him out of damp areas and practicing good hygiene in his environment.

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