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Cat has eosinophilic granuloma & stomatitis. Steroids failed, what next?

Updated On September 23rd, 2025

Pet's info: Cat | Siamese | Female | spayed | 3 years and 3 months old | 7 lbs

My cat Pippa has been diagnosed with eosinophilic granuloma. Steroids and antibiotics helped but didn't resolve. Do you think cold laser therapy or cyrosurgery would be appropriate? Do you think it looks like stomatitis too and that she should have a full mouth extraction? Thanks for your opinion.

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1 Answer

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Answered By Linda G, MS, DVM

Veterinarian

Published on April 3rd, 2018

Hello. This is definitely stomatitis. This is an extremely frustrating disease to deal with. Full mouth tooth extraction may be appropriate as this removes all the allergenic plaque present on the teeth, but some cats still suffer oral tissue lesions. Exact dental x rays need to be done to make sure no tooth roots are left behind. Have you tried cyclosporin? Some other treatments you & your vet may want to investigate include gold salts, omega interferon alpha products, coating the teeth with bovine lactoferrin, & hypoallergenic diets along with omega 3 & 6 fatty acid supplementation. CO2 lasers have been used, but mostly after extractions have been done, & finally, there is ongoing research using stem cell therapy to treat this terrible syndrome. If you have a feline specialty practice in your area or a university veterinary college, these are good places to discuss further treatment of your kitty. Thanks for using Petco Pet Education Center, formerly Petcoach.

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