Why are my dog's liver enzymes & bile acid high, and she won't eat?

Question

hello, My Puggle Lulu had her regular check up, it was discovered that she has high bile acid and ALKP numbers. She is presently taking Denamarin for medium dogs and 250 mg of Metronidazole. She was doing fine and had no symptoms. However today she did not want to eat (she ordinarily will eat anything and is always hungry.) Can you give me an idea what may be causing these high numbers. Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | 8 years and 2 months old | 32 lbs

Megan, DVM, CVA · Accepted Answer

Poor Lulu. There are several things that can cause increased liver enzymes from a liver infection (bacterial/viral), a bile duct obstruction (less likely from looking at this bloodwork), pancreatitis, cancer, and more. The increased bile acids shows that the liver isn't functioning proper right now. This could be due to an acquired shunt as well. I think she is on a good medicine regimen for now. I would try to offer her some plain boiled boneless, skinless chicken and white rice to see if this entices her to eat. If she is still refusing to eat this then she needs to be rechecked by your vet. I would talk to your vet about testing her for pancreatitis. Your vet may also want to do any abdominal ultrasound and possible aspirates or biopsy of the liver to find more information. Your vet can also give her an appetite stimulant if needed. I hope this helps!

Why are my dog's liver enzymes & bile acid high, and she won't eat?

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