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My dog with kidney disease took Metacam. Is one dose safe for her?

Updated On September 23rd, 2025

Pet's info: Dog | Italian Greyhound | Female | spayed | 10 years and 9 months old | 14 lbs

I asked a question earlier this evening and did not get a full response. My 11 year old Italian greyhound was prescribed metacam and amoxicillin for a mouth infection. She DOES have kidney issues and unconfirmed Glomerulonephritis because I won’t put her through a biopsy. I feel the metacam is dangerous but I’ve akready given her one dose before I found how dangerous it could be. I just want to know that one does of metacam will not harm her. She’s also not eating because her mouth hurts. I

2 Answers

Most Helpful Answer

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Answered By Rodrigo Roca, DVM

Veterinarian

Published on March 8th, 2018

Hello, Lola is indeed at higher risk for adverse reactions even after a single dose of meloxicam, however your veterinarian is likely not too concerned with the severity of her kidney disease. Therefore, the side effects of meloxicam to her kidneys would be dependent on how severe her kidney disease is. I would recommend monitoring her kidney values for the next five days as Meloxicam has a long half-life and can take up to 5 days to remove completely from the body. This could be done with daily blood checks. Also know that of all the NSAIDs, Meloxicam has the widest safety margin in the phase of kidney disease. Look for any signs of increased drinking, decreased urinations, lethargy, painful abdomen, vomiting, or a decreased appetite and have her evaluated immediately if you note any. Hope this helps and best of luck.

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    Answered By Andrea M. Brodie, DVM

    Veterinarian

    Published on

    I answered your question before and stated that you should not give the Metacam to your dog as she has a kidney issue ( you only mentioned unconfirmed glomerulonephritis, not that she has indeed kidney issues) I also stated that Metacam is eliminated through the kidneys and therefore you should not give it. The one dose given will not likely cause her more damage, just don't give her the rest of the medication. Ask your veterinarian to give you another pain medicine for her such as Tramadol or buprenorphine which would not affect her kidneys and facilitate her eating without pain. I hope her mouth heals soon.

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