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Why is my puppy lethargic and vomiting after her vaccine shots?

Updated On September 23rd, 2025

Pet's info: Dog | Newfoundland | Female | unspayed | 2 months and 14 days old | 19 lbs

My 12 week old Newfoundland puppy had her 2nd injections today at 3.30pm . Since then she has vomited once, mucus , and has been very lethargic and over sleepy. She has also remained outside. She has eaten a little amount but not much water either. Her nose is warm and she isn't bothered with my other dogs....which is very unusual.

1 Answer

Most Helpful Answer

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Answered By Dr. Leigh, DVM

Veterinarian

Published on December 4th, 2017

It could be a reaction to the vaccines. You should call your vet and give him/her an update so your vet knows she had a possible reaction. If she was given multiple vaccines, your vet may want to separate the vaccines next visit. If the abnormal signs last for more than 24 hours then she should be examined by your vet for treatment. She may need some fluids and an anti-inflammatory to help make her feel better. Hope she feels better soon!

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