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My dog's flea topical didn't work. Is Nexgard safe to give now?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Female | spayed | 7 years and 11 months old | 65 lbs

I gave both of my dogs dog md topical flea preventive 4 days ago and it did not help with the fleas. Can I safely give them nexguard or should I wait?

1 Answer

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on October 12th, 2017

It is better if you wait at least two weeks in between medications. Most of the tick and flea products manufacturers do not recommend using more than one preparation at the same time. It is hard to predict what side effects could develop if two similar products are used at the same time. If you want to call Nexguard's 800 number (should be on the box) and tell them what product you already applied they may tell you it's OK. Don't forget to treat the house and/or yard for fleas. This will help tremendously. I suggest Knockout Spray ES for the house and Advantage II yard spray. You can buy these online without a prescription. Also, don't forget to treat every pet in the household for fleas too!

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