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Is Benadryl safe for my cat's allergies and constant scratching?

Updated On September 23rd, 2025

Pet's info: Cat | American Shorthair | Female | spayed | 8 years and 5 months old | 12 lbs

My eight year old calico cat was diagnosed by my DVM with herpes and possible food allergies, particularly to chicken. She is given lysine powder daily as prescribed by my vet. She is constantly scratching her face, specifically around her eyes, her ears are hot. The cat is clearly uncomfortable. Would offering her 1/2 a child's Benadryl tab be advisable?

2 Answers

Most Helpful Answer

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Answered By Jessica Keay, DVM

Veterinarian

Published on June 22nd, 2017

It is always recommended to discuss any new medications with your veterinarian prior to starting, as they known your pet's history and current medications best. We sometimes use benadryl in cats, but sometimes other anthistamines we prescribe such as hydroxyzine, can be more effective. Other times if the itching is intense we may need stronger medication such as a short course of steroids or a medication called apoquel (this is off label use as it is only labeled in dogs). Sometimes we also add fatty acid supplements as well because these can decrease inflammation in the skin and help with itching. I would recommend talking to your vet and letting them know her itching is bad and she needs some medication to make her more comfortable, and they can help decide the safest/best medication for your kitty.

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Other Answers

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    Answered By Megan, DVM, CVA

    Veterinarian

    Published on

    With her weight being 12 pounds she could get 12.5mg of benadryl which is 1 teaspoon of childrens liquid benadryl, a full childrens tablets, OR 1/2 of an adult 25mg benadryl twice a day. I hope this helps and she finds some relief!

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