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Is 400mg Trazodone daily an excessive dose for my 65-pound dog?

Updated On September 23rd, 2025

Pet's info: Dog | Black and Tan Coonhound | Female | spayed | 11 years and 2 months old | 65 lbs

My 65 pound dog has been prescribed 400 mg of Trazadone daily. Doesn't that seem excessive?

2 Answers

Most Helpful Answer

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Answered By Lauren Jones VMD

Veterinarian

Published on April 14th, 2017

Trazodone has a very wide dosage range due to the variation of an individual dog's response to this medication. While Alice's dose is near the upper dosage range at 13.5mg/kg, it is still within a normal dosage range. If you have concerns about the dose or any possible side effects, please contact the prescribing vet.

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    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on February 3rd, 2020

    Yes, that dosage is appropriate; even a bit low in my opinion. This drug has a very wide dosing range and I have found that most dogs need a pretty high dose for it to be effective. Here is a link to an article about this drug, side effects, etc: ( https://vcahospitals.com/know-your-pet/trazodone )

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