My dog's high ALP after anal gland rupture: Is it Cushing's or pain?

Question

My 9 yr old Chi had a ruptured anal gland. I went ahead and scheduled a dental cleaning for a few days later and her labs came back liver enzyme ALP/1700 ALT/245. vet says it's cushings and I need to take her to a specialists. However, I'm thinking that her elevated ALP might have been due to her vomiting and not pooping due to the pain and then rupture less than 18 hours prior to labs? I'm thinking another lab might result in lower #'s or is this way off base? Pet's info: Dog | Chihuahua | Female | spayed | 8 years and 5 months old | 12 lbs

Dr Stafford, BVetMed, MRCVS · Accepted Answer

I'm sorry to hear about Chi Chi's recent issues. Vomiting and an anal gland abscess/rupture may cause some changes on the blood panel, but not typically ALP. When you have a significantly elevated ALP and normal ALT it is highly suggestive of Cushing's disease. Cushing's can be diagnosed with a few different tests, these tests involve taking blood, injecting a substance then taking blood again to see the body's ability to respond. I think it would be wise to have her checked. If she dies have Cushing's thankfully it is treatable with medication but this will be for life.

My dog's high ALP after anal gland rupture: Is it Cushing's or pain?

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