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My puppy strains to pee, had blood, no UTI. Should I be worried?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 40 lbs

Our puppy started having a few urine accidents in the house 4 days ago, then we saw her urine was tinged with blood. Her urine no longer has visible blood, and she pees normally outside but then continues to squat a few times after without urine coming. The vet said her urinalysis does not show a UTI, had elevated blood levels from inflammation. I opted for the antibiotics and cranberry supplements, started Mon evening. The vet wasn’t concerned but we’re nervous there’s something serious?

1 Answer

Most Helpful Answer

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Answered By Jessica Desrosiers

Veterinary Technician

Published on July 13th, 2022

Sterile cystitis (inflammation without bacteria present) can occur sometimes. I would see how Korra does on the medication and after the course of meds is done schedule a recheck UA to see if the blood and inflammation have resolved. If her symptoms continue, worsen, or the UA shows no changes, investigating for other causes behind it with additional tests such as ultrasound or X-rays may help determine what is going on. Sometimes, tumors or cysts can cause bladder irritation, however, these are less common in very young dogs. Diet can also play a factor, so if no other apparent causes are found, trying an inflammation-friendly food from your vet may be a good option.

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