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Puppy vaccination timeline: When is the best time for first shots?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | spayed | 5 years and 11 months old | 8.15 lbs

Hi there...my dog had a C sections this Thursday and I've been told that the puppies have to be vaccinated once they get 1 month old. I am afraid that is going to be a bit too early as everywhere on the internet it says they must be vaccinated at 6-9 weeks old. I have to mention that we had a puppy who died of distemper a few months ago and maybe the bacteria is still in our garden. What do you recommend? Many thanks!

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1 Answer

Most Helpful Answer

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Answered By Jenna Beyer, DVM, MBA, cVMA

Veterinarian, Certified Veterinary Acupuncturist

Published on August 29th, 2021

I would start at 6 weeks of age if their mother was properly vaccinated. If she was, she has passed on antibodies to the puppies. If she wasn’t properly vaccinated, you could consider starting vaccines at 4 weeks of age if the label for the vaccine says it is safe to start then (each vaccine brand is a little different on when the vaccine can be used).

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