My dog has high-grade MCT spread to lymph nodes. What's the prognosis?

Question

My dog lost her ear to remove MCT(High Grade) 2nd surgery, biopsy result was ok but It came back on her prescapular lympnodes within a month, spread from original site. It was Too late, but we started Palladia. Our Doctor said that she can be good for;- as worst-6wks to the best-4 months. I searched but couldn’t find any data. Generally speaking, MCT spread to Lymph nodes, what’s the survival rate? Even taking Palladia, (and Chinese herbs), the miracle would not happen? Please kindly advise. Pet's info: Dog | Mixed Breed | Female | spayed | 10 years old | 56 lbs

Lauren Jones VMD · Accepted Answer

I'm so sorry to hear that you and Tsunami have been through so much lately. Unfortunately, high grade mast cell tumors have a pretty guarded prognosis - a survival time of 4 months is the average with surgery alone. From my research, metastasis to the lymph nodes does not markedly impact expected survival times with high grade tumors, but it would change things if she had a low grade tumor. Chemotherapy (including Palladia) may help to slightly prolong her survival, but there are so many variables at play (i.e. specific mutations in her tumor, as well as Tsunami's currently quality of life) that it's hard to comment more specifically. If you want to do everything possible, I'd recommend consulting a veterinary oncologist. Even then, they won't be able to cure her cancer, but will try to manage it to prolong her survival time while maintaining her quality of life. Ultimately, try to make any decisions based on Tsunami's quality of life. This resource has a lot of good information with respect to evaluating her quality of life: https://vet.osu.edu/vmc/sites/default/files/import/assets/pdf/hospital/companionAnimals/HonoringtheBond/HowDoIKnowWhen.pdf. Best of luck with everything. I hope that everything goes as well as possible.

My dog has high-grade MCT spread to lymph nodes. What's the prognosis?

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