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Can I safely combine Simparica and K9 Advantix for my dog's fleas?

Updated On September 23rd, 2025

Pet's info: Dog | American Pit Bull Terrier | Male | unneutered | 4 years and 7 months old | 40 lbs

Is it safe for me to use simparica oral flea medication and k9 advantix I topical flea medication together?

2 Answers

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on May 1st, 2018

Generally, we at Pet Coach recommend using one flea and tick medication. I would recommend only using the K9 advantix on Pistol. It kills fleas, repels fleas, kills flea egg and larvae, kills ticks, repels ticks, and kills and/or repels mosquitoes. Simparica only kills fleas and ticks. You will get everything you need for Pistol's protection with the K9 advantix. I hope this helps!

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1Pet Parents found this answer helpful

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    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on October 26th, 2019

    You really should only need one or the other product. Putting both products on at the same is not recommended. If you are using Advantix II and you are still seeing fleas then I suggest you switch to another flea prevention.

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    1Pet Parents found this answer helpful

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