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Cats lethargic and not eating after vaccinations. Is this normal?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Male | unneutered | 1 year and 6 months old | 10.8 lbs

Hi My name is amber I have two cats Jerry and Midnight and they both got there vaccinations done yesterday. They got the FVRCP, FELV, Dewomer, and Rabies Rabvac3. So before the shots where taking when they was at home they was playful and after their shots they are not as active as before and they only at after they came back from getting there shots I have not seen them eat since then. What do I do I am worried. Jerry not playing with his favorite toy like he use to

1 Answer

Most Helpful Answer

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Answered By Penelope Graben, DVM

Veterinarian

Published on September 29th, 2019

Hello, Mild lethargy and change in behavior can be normal up to two days after vaccinations. This is because the immune system is working to build protective immunity and the cats are stressed about the car ride and vet trip. Signs of a serious allergic reaction to vaccines include: facial swelling, hives, vomiting, and diarrhea. Those signs would be a reason to go to the vet ER. I hope this helps. Thanks for using Petco Pet Education Center, formerly Petcoach.

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