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Could my dog's high cholesterol or ALP cause bladder stones?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | 11 years old

Is there any conection between high level of holesterol and high alp (other ok) and oxalate or struvite stone in bladder? Thank you in advance.

2 Answers

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on July 24th, 2019

Not that I am aware of. The exact cause of calcium oxalate bladder stones is poorly understood at this time. Normal dog urine is slightly acidic and contains waste products from metabolism including dissolved mineral salts and other compounds. These mineral salts will remain dissolved in the urine as long as the pH stays within a narrow range, and as long as the urine does not become too concentrated. Some diets that cause a persistently alkaline urine pH may also cause this. This link may help you more. ( https://www.vetmed.umn.edu/sites/vetmed.umn.edu/files/canine_calcium_oxalate_uroliths.pdf )

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  • Image profile

    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on

    Not that I am aware of. The exact cause of calcium oxalate bladder stones is poorly understood at this time. Normal dog urine is slightly acidic and contains waste products from metabolism including dissolved mineral salts and other compounds. These mineral salts will remain dissolved in the urine as long as the pH stays within a narrow range, and as long as the urine does not become too concentrated. Some diets that cause a persistently alkaline urine pH may also cause this. This link may help you more. ( https://www.vetmed.umn.edu/sites/vetmed.umn.edu/files/canine_calcium_oxalate_uroliths.pdf )

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