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My large dog ate ibuprofen. What should I do if vets are closed?

Updated On September 23rd, 2025

Pet's info: Dog | English Mastiff | Female | 160 lbs

My mastiff is btw 150 and 200 lbs. Ate 2 600 mg motrin no vet around me is open. What should I do.. no symptoms so far

2 Answers

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on June 8th, 2019

Hi there. In an otherwise healthy dog, the toxic dose of ibuprofen is considered to be anything above 25 mg/kg. If your dog is 150 to 200 lbs (68 to 90 kg), this would mean she got a dose of 13-17 mg/kg. This is below the toxic dose, so as long as your dog doesn't have any other health issues and is not taking any other medication such as a steroid or NSAID, it's unlikely to cause any significant issues. To be on the safe side, you should monitor for any vomiting (especially with blood or "coffee grounds"-like material), lethargy, or loss of appetite over the next couple of days, and take Shawnee to the vet for an exam if you have any concerns.

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on May 26th, 2018

    Hi there. Assuming that it was a 200 mg tablet, meaning that Daisy got 100 mg of Advil, this would not be expected to cause any problems provided that she's healthy otherwise, and not currently on any other meds. The toxic dose of ibuprofen in dogs is 50 mg/kg, and Daisy only got about 7.5 mg/kg based on her weight.

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