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My cat has EPI, not eating. Should I discuss pain meds with my vet?

Updated On September 23rd, 2025

Pet's info: Cat | American Shorthair | Female | spayed | 15 years and 11 months old | 7.5 lbs

My cat has EPI (exocrine pancreatic insufficiency). I understand when people get this there is pain involved but my vet didn't prescribe anything for pain. My cat has lost a lot of weight and doesn't want to eat much. She gets enzymes in every meal. I think she needs something for pain but going to the vet is very traumatic for her. Do you think I should pursue pain meds or stick to anti nausea meds like cerenia? She also gets a small amount of prednisolone. Pills are crushed and added to food.

1 Answer

Most Helpful Answer

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Answered By Lindsey Edwards MVB, BSc, IVCA

Veterinarian

Published on March 31st, 2018

Please contact your vets office to discuss her specific case - primary EPI (reduced function or pancreatic volume) is seldom painful in contrast to inflammatory pancreatitis. Pancreatitis itself can result in scarring and reduced function requiring additional enzyme supplementation. Prednisolone has some antiinflammatory properties and many pain medications cannot be combined with this so a risk benefit judgement must be made in consultation with the treating vet in order to determine to safest and most effective management of such a complicated condition

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