My dog with lymphoma is sick. Is it a relapse or chemo side effects?

Question

F,7 yo,neutered,16.6 kg,has DCM & spondylosis, previously diagnosed with Lymphoma, had chemo & Metyl-prednisolone. Symptoms:fever,bloody diarrhea,moderate anemia,muscle atrophy,reactive submandibular nodes,inflammation on the muzzle;dehydrated,anorexic,poor appetite.Tested negative for HepatozoonCanis,Toxoplasma,Babesia,Helicobacter;histopathological exam of node aspirate and blood smear also negative for neoplasm.Currently on Metronidazole 250mg x 2/day & IVs. Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 36.59 lbs

Stacey Anstaett, DVM · Accepted Answer

I'm sorry Eva is having trouble. I am worried that Eva's "previously diagnosed lymphoma" may be the major issue here. I don't know if you are saying that she was previously diagnosed and treated with chemo and went into remission, or if she is currently receiving chemotherapy for a very recent diagnosis. If she was treated previously and was in remission, she could be coming out of remission. While lymphoma is responsive to chemotherapy it will eventually always relapse. If she is currently receiving chemo for lymphoma, some of her symptoms (GI upset, anemia) could be due to the treatment. If you would like to have a consult, I may be able to further assist you since it sounds like she's a bit of a complicated case. I hope that's helpful. Thank you for using Petco Pet Education Center, formerly Petcoach and I hope Eva gets to feeling better.

My dog with lymphoma is sick. Is it a relapse or chemo side effects?

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