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My cat has a persistent, painful tongue ulcer. What's the cause?

Updated On September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 5 years and 3 months old | 11 lbs

Hi, my cat has a large inflamed ulcer on his tongue. It has persisted for about 6 months now, with frequent visits to my Vet who cannot identify the cause. He says what is peculiar is that it is localised to the tongue only. An initial program of Cortisone injections seemed to clear it up. But then it returned a month later. Now, subsequent Cortisone injections seem to have no effect. It looks very painful. Any ideas? I would be most grateful.

1 Answer

Most Helpful Answer

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Answered By Dr. Massimo Orioles, DVM, Cert AVP, MRCVS

Veterinarian

Published on February 21st, 2017

Calicivirus infection can cause this kind of signs and not respond to steroids. A sample obtained by a swab from the lesions can easily identify that. If negative a sample from the lesions (biopsies) is needed. Antibiotics may be needed. I would recommend to discuss these options with your veterinarian.

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