Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 10 years old | 87 lbs
Lab/Great Dane mix with tumor on right rear femur causing some limping. Biopsy performed. Lab results did not indicate action plan. Have a good vet but he has no action plan except taking another biopsy for the lab. Lab results follow: No inflammation or neoplasia. Mild fibrosis and hemosiderin inspecific as to cause. Deeper histologic sections noted area of periosteal fibrosis, Observed osteoclastic resorption. Specimens not from area of lysis. Neither inflammation nor neoplasia is evident.
1 Answer
Published on January 29th, 2017
Poor Diablo! I'm sorry to hear that he's having this problem. If I'm understanding you correctly, it sounds like he has a bone tumor of some kind affecting his femur - I'm assuming that this was diagnosed on x-ray, along with the physical exam. Statistically, by far the most common type of bone tumor in a dog of this age and breed is an aggressive cancer called osteosarcoma - it's best to confirm this with a biopsy if possible, but it can be very difficult to get a diagnostic sample of a bone tumor without special equipment. If you want to try and get a definite diagnosis, I would suggest asking for referral to a specialist who can take a full-thickness bone biopsy with special tools. If referral isn't something you want to pursue, I would recommend asking your vet for treatment recommendations at this point based on the presumptive diagnosis of osteosarcoma - this might include amputation of the affected leg, and/or palliative treatment with anti-inflammatories and pain medication to make him more comfortable.
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