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My dog's tumor was benign. Can it become cancerous and cause vomiting?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 6 years and 1 month old | 95 lbs

My 5ish year old Rottweiler/mastiff mix has what I think is a mast cell tumor. A year or two ago my vet took a sample in-house and said it wasn’t cancerous. The last month or so, this dog has been vomiting occasionally, and I was wondering if this could be related. Can a tumor that was once non cancerous become cancerous?

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1 Answer

Most Helpful Answer

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Answered By Makenzie Kurth, DVM

Veterinarian

Published on February 24th, 2018

Thanks for using Petco Pet Education Center, formerly Petcoach! Overall, from what I'm reading and seeing, I have a low level of concern about Mukwa. This lesion does not look typical of a mast cell tumor (though that type of cancer does not always follow the "rules"). In general, non-cancerous things do not become cancerous with time - though there are exceptions. Occasional vomiting is not necessarily something I equate with Mast Cell Tumors, but does warrant a chat with your vet to see if it's something worth looking into. More concerning signs to me would be decreased appetite, weight loss, or lethargy. Best of luck to you and Mukwa!

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