Is Mycophenolate good for dog kidney failure after Ehrlichia?

Question

Burt (9 month, mixed dog) was diagnosed a few weeks ago with Ehrlichia and acute renal failure. He spent 5 days in the hospital. His kidneys had started to show improvement but, as of yesterday they are at a 4.2 even though they improved last week to a 3.2. Every day I give him 350 ml of lactated ringers, plavix, doxycycline, prednisone, and enrofloxacin. Our vet suggested that we now put him on Mycophenolate. The vet suspects post-infectious glomerulonephritis. Is this a good treatment?

Laura Johnson VMD · Accepted Answer

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! Poor Burt! It is hard to guide you with out seeing Burt's blood work and urine samples. Ehrlichia is an odd tick borne disease to cause kidney disease. That is usually Lyme. If your Vet is suspicious of glomerular nephritis, aka GN (low albumin, increased kidney values, protein in the urine) then immunosuppressivies are sometimes added to the treatment plan, which mycophenolate is. I have used Mycophenolate for Immune mediated hemolytic anemia but not for GN. Mycophenolate is newer and is becoming more of a go to drug for things like this. If Burt has protein in his urine then consider an ace inhibitor (benazapril or enalapril) or Losartan. And be sure they have checked his blood pressure. I would trust your Vets opinion on Burt's care. I hope this helps and I wish Burt the best!

Is Mycophenolate good for dog kidney failure after Ehrlichia?

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