Updated On September 23rd, 2025
Pet's info: Cat | American Shorthair | Female | spayed | 6 years old | 13 lbs
Okay...help us with more details. Are male calico cats sterile? Can two orange tabby cats breed?
1 Answer
Published on January 30th, 2018
Male calicos are usually sterile because the gene for the black is carried on one x chromosome and the orange on another x chromosome, so, in order for a male calico to exist, it is because he has xxy chromosomes, not the typical xy combination. Only one in 100,000 male calico cats are estimated to NOT be sterile. Yes, two orange tabby cats can breed and produce offspring.
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