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My cat has fleas. Which is better: Advantage or Frontline?

Updated On September 23rd, 2025

Pet's info: Cat | Mixed Breed | Female | spayed | 3 years and 7 months old | 9 lbs

My cat has fleas. Whats better advantage or frontline?

4 Answers

Most Helpful Answer

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Answered By Kevin Sanada, DVM

Veterinarian

Published on January 15th, 2018

They are both equally as good for controlling fleas. Some people prefer one versus the other, but as far as the evidence goes they both work well to kill fleas. Frontline has the advantage that it also kills ticks. The advantage II also has this capability though. You may consider getting them both and seeing if you see a difference form month to month. Treating for fleas is not just restricted to the host, because fleas can reproduce and nest in the environment and continually cause an issue. Below is a link to a short article that explains treating the cats and environment for fleas: https://www.petcoach.co/article/5-tips-to-get-rid-of-fleas/ I hope that helps and all is well with Luci.

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Related Answers from Veterinarians

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    Answered By Lauren Jones VMD

    Veterinarian

    Published on February 25th, 2018

    Frontline Plus is meant to be used as a single dose applicator for an individual animal. It is not recommended to split doses since it is exceedingly easy to over or under dose animals. If you are looking to use Frontline in a more cost-effective manner for multiple animals, I would instead consider using a Frontline spray ( https://www.drsfostersmith.com/product/prod_display.cfm?pcatid=15694 ). That said, I do not find Frontline to be among the more effective flea preventatives on the market currently, and I generally recommend using Advantage, Comforts (prescription-based), Bravecto (prescription-based), or Revolution (prescription-based) instead. I hope this helps and that all goes well!

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  • Published on October 10th, 2017

    Yes that sounds like you cat might be having fleas so no harm at all if you want to start the treatment with appropriate dosage of one of the two. I would suggest to go for Advantage though as Frontline seems not working so well at the moment. Please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on July 3rd, 2018

    Poor kitty! It does sound like the Advantage may be causing some skin irritation when it's applied, so I agree that it would be a good idea to try something different next month to see if he tolerates this better. It's true that Frontline does not work well in my experience, so I would recommend trying Revolution or Bravecto instead - you can get these from your veterinarian, and both are very safe and effective.

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    1Pet Parents found this answer helpful

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