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Why won't my kitten's URI symptoms clear up after antibiotics?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Male | 6 months and 7 days old | 1.5 lbs

I have a 6 month old foster that ive had since he was about 10 weeks. This is due to the fact that no matter how many times I treat him and how many different antibiotics have been tried, his URI symptoms of watery eyes and sneezing won't seem to go away. I've tried at least 2 rounds(with a vets direction) of amoxy, clindamycin, clavamox and doxycycline. I've also been doing tobramycin drops to no avail. I have also been giving him lysine in all his food since I got him. Why wont he clear up?

1 Answer

Most Helpful Answer

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Answered By Kevin Sanada, DVM

Veterinarian

Published on December 21st, 2017

This is definitely something that happens where the infection is refractory to various medications. This is likely due to a couple of different factors and could indicate that this kitten doesn't have a well-functioning immune system. Considering multiple medications have been used without success, it means that the medications were either not specific to the underlying infection, or were not given long enough. Sometimes it takes months of treatment until the infection is completely treated. In order to get the necessary information to treat this successfully, your vet would need to do some tests to identify the specific cause. They may also need to test for diseases like FIV/FeLV. I hope that helps and the kitten gets better sometime soon.

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