My dog overdosed on doxycycline and has bloody stool. What now?

Question

Yesterday I gave Chiyo by mistake double dose of doxycycline (around 35 mg).. Today he showed symptoms of mild upset stomach like vomiting & loose stool.. Now i saw mucus & blood in his loose stools, is it still a side effect of the overdose? And should I continue giving him the med especially that more than 24 hours has passed? Pet's info: Dog | Pomeranian | Male | unneutered | 3 years old | 3.3 lbs

Kevin Sanada, DVM · Accepted Answer

Doxycycline can be irritating to the stomach and intestines and can cause ulceration at normal or high doses. Vomiting and loose stool indicate that there is an adverse reaction to doxycycline and blood in the stool is very concerning. A dose of 35mg is almost 5x the necessary dose, so it's understandable that this could happen. I recommend to not give anymore of the doxycycline and to take Chiyo to a vet for an evaluation and treatment soon. It's likely that he has an ulcer in his stomach and intestines. The vet will be able to better assess him and give some medication to help get him through this. I hope that helps and Chiyo gets better soon.

My dog overdosed on doxycycline and has bloody stool. What now?

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