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My dog took Fluconazole. Will it cause seizures or other side effects?

Updated On September 23rd, 2025

Pet's info: Dog | German Shepherd | Male | unneutered | 1 year old

earlier to treat his yeast infection vet prescribed him fluconazole vourse so he has to eat 2 fluconazole in one day for 6 days therefore till now he has eaten total 12 FLUCONAZOLE tablets of 150mg so will that much of FLUCONAZOLE that is 1800mg in 6 days will going to cause any side effect like SEIZURE in coming days or in future or somewhere later in life ? Does FLUCONAZOLE 150mg has any SEIZURE side effect?

3 Answers

Most Helpful Answer

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Answered By Dr. Leigh, DVM

Veterinarian

Published on December 9th, 2016

Fluconazole has been found to be very safe in dogs and the most common side effects are loss of appetite, vomiting, and diarrhea. Seizures are not a common side effect of Fluconazole. If your dog is healthy and took the fluconazole with no problems than it is unlikely to cause seizures in the future.

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Other Answers

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on November 28th, 2016

    No, Fluconazole does not cause seizures. It has fewer adverse side effects in dogs than other anti-fungal drugs used in dogs. If you have concerns about using it in Bruno, I would speak to the vet who prescribed it for him.

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    Answered By Destini R. Holloway, DVM

    Veterinarian

    Published on November 30th, 2016

    Seizures are not listed as an adverse effect of giving any pet Fluconazole. I am unsure why sources you read that indicated this but according to the Plumbs veterinary drug handbook these are the only listed possible side effects of this medication- "Fluconazole is well tolerated in the majority of dogs and cats treated. Occasionally, inappetence, vomiting, or diarrhea has been reported. Hepatotoxicity is possible and approximately 15-20% of dogs treated long-term may have increased ALT concentrations. Occasionally ALT increases will worsen necessitating fluconazole discontinuation. In humans, side effects have been generally limited to occasional GI effects (vomiting, diarrhea, anorexia/nausea) and headache. Rarely, increased liver enzymes and hepatic toxicity, exfoliative skin disorders, and thrombocytopenia have been reported in humans."

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