Petco Text Logo
Petco Pet Logo

My cat has fleas after Advantage II. Can I reapply it in 48 hours?

Updated On September 23rd, 2025

Hi! I just got a new cat, and he came with some fleas. I applied the Advantage II gel on Monday, it was supposed to kill fleas in 12 hours. today he still had them. I took him to a groomer with a flea dip and vacuumed the whole house. came back and found two living ones on him. I know that the most you're supposed to apply Advantage is a week apart, but if I didn't get enough on his skin, is it safe to apply 48 hours apart? thanks

1 Answer

Most Helpful Answer

Image profile

Answered By Vanessa Yeager DVM MPH

Veterinarian

Published on September 5th, 2017

Hi and thank you for your question on Petco Pet Education Center, formerly Petcoach! Advantage II is not safe to use twice in 48 hours. The product safety specifications indicate that it should not be applied more often than once every 7 days for cats. I would not want to overload her system with more topical product in case she received a full dose and all of the dose was absorbed. In a week, it would be okay to apply another application. Hope this has helped!

Vote icon

1Pet Parents found this answer helpful

image
Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Sponsored