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Do my dog's blood test results and meds point to Cushing's Disease?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 10 years and 1 month old | 67 lbs

Does an ALKP level of 2,000, an ALT of 135, Sodium 165, Lymphacyte .82, HCT 7, MCV 44,74, MCHC 28.4, PLT 581, PCT .52 cause you to suspect Cushings Disease? Our sweet Riley has been taking Apoquel for over a year, and Fluconazole for Valley Fever for almost a year. I am desperate for an opinion. We don't have any more money to put into expensive treatment. Please offer your understandably non-binding opinion. Thank you!!!

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1 Answer

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Answered By Stephanie Echols, DVM

Veterinarian

Published on August 9th, 2017

Riley is a beautiful dog! And elevated ALP is suspicious of Cushings but not definitive for it. Cushings is a diagnosis based on blood work AND clinical signs. The signs are a pot belly appearance, hair loss on the sides of his abdomen and hips, panting, increased appetite, increased drinking, and increased urination. If you aren't seeing these other signs, it may be unlikely she has it. The elevation could be caused by the medications she's on. I hope that helps! Kisses to Riley!

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