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My puppy is vomiting and has diarrhea after shots. What should I do?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Female | unspayed | 2 months old

My puppy got her first 5 shots on july 14 2017. I noticed she has diahrea and also there is mucus in it she also vomited yesterday morning once and it was the food she had ate. Is ihat normal? What should i do?

4 Answers

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on July 18th, 2017

Vomiting and diarrhea within a couple days of vaccinations is a sign of a vaccine reaciton. I would notify your vet about Addi's symptoms right away and then have her seen for medicaitons to stop the reaction. Also her record should now reflect hat she has a vaccine allergy and premedication can be given at her next round of shots to hopefully stop this from happening in the future. I hope she feels better soon. Take care.

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Other Answers

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    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on September 4th, 2017

    I would not be worried at this stage. It is likely a reaction to the vaccinations. Be sure to tell your vet his symptoms when he goes to get his next round of boosters. That way they may split up the vaccinations so he doesn't get so many at once. That may help. Usually these symptoms will resolve on their own. For now, just monitor him and if he seems to act sick (lethargic, not eating, not drinking, etc) then take him to your vet for an exam. If he is sick he could be showing of signs of parvo or another viral disease. Hope this helps. Best wishes!

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    Answered By Kevin Sanada, DVM

    Veterinarian

    Published on August 8th, 2017

    This is not expected and given that your dog recently had a vaccine, this is likely an allergic reaction to it. It's best you take her to the vet now, so they can give her some medicine to prevent the reaction from getting worse. It's best if you can take her to the vet office where she got the vaccine. Also, you want to note exactly what the vaccine was. First, the veterinarian should report the vaccine reaction to the manufacture. Second, you want to make sure that the next vaccine (if needed) of that type is given with an antihistamine to prevent another reaction. I hope Millie feels better soon.

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    Answered By Ricardo Fernandez, DVM

    Veterinarian, Veterinary Oncology Resident

    Published on February 2nd, 2018

    Thanks for using Petco Pet Education Center, formerly Petcoach! I do think that it could be the shots. However, your veterinarian does know his medical history better and in more detail. Possible side effects after vaccines include pain at the injection site, lethargy, diarrhea, inappetence and general discomfort. This should subside within 1-2 days. If it does not improve or it worsens, have Peppa evaluated by a veterinarian for further assessment and treatment. Otherwise, Peppa will likely start feeling better shortly. Good luck and best wishes!

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