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Why do my dog's creatinine levels fluctuate? Is it kidney disease?

Updated On September 23rd, 2025

Pet's info: Dog | German Shepherd | Male | unneutered | 4 years and 4 months old

His creatinine came 1.15 and next day when I again went for blood work it came 0.9 so why just in a day it came down automatically why there’s an fluctuation? I have notice sometimes it came elevated and sometime normal so why so ? Any idea ? His BUN value came 14 both time

1 Answer

Most Helpful Answer

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Answered By Dr. Elizabeth

Veterinarian

Published on March 20th, 2020

Blood levels likely fluctuate every day for all pets and people. It's possibly related to how much water he has drank (or moisture in the food) and possibly what time and how much he has eaten within the last 12-24 hours. I recommend to have an additional test called an SDMA run. This test will accurately predict if kidney disease will develop within the next 18 months in about 95% of pets. Bruno should also be having his urine specific gravity tested along with his kidney values as you need to know all the values in order to know if kidney disease is a concern or not. For example, a dog with a higher CREAT and extremely concentrated urine is likely a little dehydrated. Where as a higher CREAT and not so concentrated urine may have kidney disease. I hope this helps.

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