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My dog strains to pee, no stones, no improvement on meds. What now?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 1 year and 10 months old | 72 lbs

Have a 1 year old retriever. Has been frequently urinating and straining to pee. Vet orig diagnosed with stones. Today got X-ray - no stones. He’s on amoxicillin still and hills food c/d now and showing no improvement. What should I do/look for? Very nervous.

3 Answers

Most Helpful Answer

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Answered By Angel Alvarado, LVT

Licensed Veterinary Technician

Published on March 4th, 2020

There may be some residual inflammation related to the stones. He may also have urinary crystals which may also be irritating. Dis uss anti-inflammatory or pain medi ation with your veterinary. Having either on board may make Watson more comfortable. A sterile urine sample should be collected and submitted for urinalysis, culture and sensitivity. If he has a UTI, the culture will confirm it. The sensitivity panel will determine the most effective antibiotic to use in treatment. It may be that any potential bacteria are not susceptible to amoxicillin.

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    Answered By Dr. Dayna, DVM, CVA

    Veterinarian, Certified Veterinary Acupuncturist

    Published on March 22nd, 2018

    In these difficult cases I will usually take an x-ray to make sure that there are no bladder stones present, then I will culture the urine to determine what bacteria is present and what antibiotic would be most successful. Occasionally a special diet is needed but not always. Best of luck and I hope she improves soon. Thank you for using Pet Coach.

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    Answered By Claudia Fioravanti

    Veterinarian

    Published on March 10th, 2019

    Yes, I agree with you even if crystals were found, it is always recommended to exclude a bacterial infection with culture and sensitivity to rule out and treat a possible concomitant infection. Continue the same urinary diet. Hope this helps !

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