My dog has high liver enzymes; is doxycycline safe or harmful?

Question

My 14 pound dog Casper liver counts came back alt 296 and alkp >2000. All Other values in normal range. My vet put him on doxycycline 50mg for 28 days. When I lockup the side effects, liver damage and elevated enzymes are listed everywhere. I called him again and he said it often helps the liver. Help! I am confused. He has been on denamarin for a year. Pet's info: Dog | Bichon Frise | Male | unneutered | 12 lbs

Stacey Anstaett, DVM · Accepted Answer

If there is an indication for the doxycycline, as it sounds like your vet suspects there is--meaning your vet suspects that there is a bacterial infection that may respond to doxycycline-- then it is appropriate. Ideally, a more definitive diagnosis would be reached. Has Casper had an abdominal ultrasound? Is he showing symptoms of illness and that is why your vet ran the bloodwork in the first place? I presume that Casper has a history of elevated liver values since he has been on Denamarin. It may be beneficial to consider a consultation with an internal medicine specialist. Their advanced training and focus on diseases of the internal organs make them an extremely valuable resource in difficult cases. Find one here: https://find.vetspecialists.com/

My dog has high liver enzymes; is doxycycline safe or harmful?

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