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My dog has explosive diarrhea, not eating, and meds aren't working?

Updated On September 23rd, 2025

Pet's info: Dog | Border Terrier | Male | neutered | 13 years old | 20 lbs

Jack has IBS. We visited friends & he ate the cat food & got a tick that wasn’t found for a week. He has explosive diarrhea since the 30th & the medication, endosorb, that I’ve given him since the 4th has not helped At all. Yesterday the vet gave me metronidazole & I also gave him Imodium ad. still no difference. Tonight I got purina pro-plan veterinary diets ‘EN’, but since yesterday, he has stopped eating. He licked his poo tonight though. ALL of his blood work & stool came back clean.

1 Answer

Most Helpful Answer

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Answered By Sara Farmer, DVM

Veterinarian

Published on January 8th, 2020

There are several things I try for diarrhea that is not responding to typical treatments - sometimes I give the medications for a longer duration, sometimes I'll try a different antibiotic, and sometimes I'll try a different diet (which it sounds like your vet is attempting with the EN). Your vet might also want to retest a stool sample - sometimes with diarrhea there just isn't enough actual feces to get a positive results. Chronic diarrhea can also be caused by inflammatory bowel disease which is a more severe form of IBS and ultrasound and special blood testing can help diagnose this. Corticosteroid medications and B12 injections are often the recommended treatments for IBD.

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