Updated On September 23rd, 2025
Pet's info: Dog | English Springer Spaniel | Male | neutered | 7 years and 6 months old | 60 lbs
My dog has been diagnosed with lupus and prescribed Niacinimide and Doxycycline. I'm worried that the dose of Doxycyline is too high - 500 mg three times daily, since everything I've read online indicates a much lower dose. Is this too much?
1 Answer
Published on November 27th, 2019
Hello. I wonder if perhaps the labels were mixed up. Normally, Doxycycline would be prescribed at 5-10 mg/kg ( 136-272 mg ) every 12 - 24 hours & the niacinamide 500 mg every 8 hours. Now if your vet actually sent home tetracycline, then the dose would be 500 mg every 8 hours. But if the Doxycycline was substituted for the Tetracycline, then the total dose should be less. I would definitely double check this with your veterinarian as soon as possible. Thanks for using Petco Pet Education Center, formerly Petcoach.
1Pet Parents found this answer helpful
Book an appointment with the pros – our expert vets are here to help.