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My dog's Frontline Plus isn't working. Should I switch to Advantix?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Small (up to 22lb) | Male | neutered | 11 lbs

What is the difference between advantix and frontline plus? I've ordered frontline plus but am worried by some reviews that it doesn't work well. Should I use advantix instead? Right now, I'm using frontline spray.

1 Answer

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on November 19th, 2019

The difference is that Advantix kills and repels fleas, ticks and mosquitoes, kills lice and also repels biting flies. In comparison, Frontline kills but does not repel fleas, ticks or lice and has no effect on mosquitoes or biting flies. Now, that being said, I've also had many cases where Advantix treated dogs still came in with ticks on them and dogs with Frontline had less occurrence of this happening. The spray is for spot treating and is different than using the monthly preventive. Either preventive is fine to use. If you notice ticks still or fleas, then switch to a different product would be my recommendation. I hope this helps!

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