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Can I give my dog olanzapine for occasional separation anxiety?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Male | unneutered | 4 months and 19 days old | 40 lbs

Can I give my 40lb dog with separation anxiety some olanzapine (and how much?) before I leave when I’m going away for a few hours? It would only be occasional every couple weeks or so.

1 Answer

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on May 11th, 2023

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. There is no FDA-approved use for atypical antipsychotics such as olanzapine in veterinary medicine although they have been used to treat dogs with aggression. If you need something to give Spark occasionally for separation anxiety you need to speak to your vet about getting him something. Olanzapine is not recommended.

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