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My dog had a seizure and is on Prozac. Is it safe to continue?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 3 years and 3 months old | 85 lbs

My dog recently had a focal seizure (never had a seizure before) and during the vet visit he was prescribed Prozac. I've read Prozac shouldn't be given to dogs with a history of seizures. Should I stop giving it to him? He's 85 lbs and is taking 40 mg a day (is that considered a high or low dose?)

1 Answer

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on January 6th, 2023

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. I'm so sorry but I'm not fully understanding why the Prozac was prescribed. For an unrelated issue or to lessen anxiety to prevent more focal seizures? Typically Prozac (fluoxetine) is dosed at 0.5 to 0.9 mg per pound orally once per day. So for an 85 pound dog 40mg is actually a touch under the lowest part of the dosing range. First you need to understand why the Prozac was prescribed (for what condition) and then talk to your vet more in-depth about its use in Thor's case. I would not personally be concerned about using this low dose of Prozac in a dog with a history of only one focal seizure. Do not abruptly stop giving Prozac unless he has only been on it a few days. They must be weaned off slowly. So again, my recommendation is that you speak to your vet. Hope this helps. Best wishes.

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