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My dog takes Ursodiol for liver issues. Can it cause or worsen diabetes?

Updated On September 23rd, 2025

Pet's info: Dog | Miniature Schnauzer | Female | spayed | 10 years and 6 months old | 17 lbs

My dog is on Urisodil and Denamarin for abnormal liver functions. She has been diagnosed with Diabetes and we are presently giving her 2 doses of 5 units of insulin twice a day and checking BG. My question is since Urisoodil causes Diabetes in People could it cause diabetes in dogs. Don't want to hurt her trying to help her. thanks

1 Answer

Most Helpful Answer

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Answered By Lauren Jones VMD

Veterinarian

Published on April 6th, 2022

While I can't speak to ursodiol's side effect profile in people, I can tell you that ursodiol does not cause diabetes or exacerbate existing diabetes in dogs. Continue working closely with Mindy's vet to regulate her diabetes and liver dysfunction. I don't see any contraindications or interactions between insulin, ursodiol, and Denamarin. Best of luck with everything!

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