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My dog has a high-grade mast cell tumor with incomplete margins. What now?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | spayed | 9 years and 10 months old | 56 lbs

My baby diagnosed today, Mast Cell Tumor grade II,- High Grade (kiupel system) Mitiotic count greater than 30. Margins appears incomplete Neoplasticism MCell present at nearest submitted ventrilateral margin. My vet didn’t give me clear answer what we can do. What do you recommend to do? Re-surgery (MCT at right ear) cut off ear? Quimo? Or don’t fight anymore? Please help and kindly advise,, I am just ok to hear your thoughts.

1 Answer

Most Helpful Answer

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Answered By Anna M., DVM

Veterinarian

Published on May 4th, 2021

I’m sorry to hear about Tsunami’s diagnosis. MCTs are quite common in dogs, and unfortunately due to the cell distribution around the primary tumor, incomplete margins are common. If you want to be confident you’re pursuing the best options for the best prognosis, I recommend asking your vet for an oncologist referral. A veterinary oncologist will be the best specialist to be able to present all the options and their given pros & cons, and they have access to chemo medications that most primary vets don’t carry. If you choose not to pursue referral, then I recommend reaching out to your vet again to discuss the next step. If this were my case, I would probably recommend sampling Tsunami’s lymph nodes with a needle to look for evidence of regional metastasis, and based on those findings discuss if a second surgery is appropriate. Hope this helps!

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