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How can I safely wean my dog off prednisone and methocarbamol?

Updated On September 23rd, 2025

Pet's info: Dog | Bichon Frise | Female | spayed | 17 lbs

My dog is taking 5mg of prednisone every 12 hours. She has back issues but is much better but the Vet didn’t give weaning instructions and went out of town. Can you give me weaning instructions please? She is also taking methocarbamol so I’d like to get her off of that if you have guidance I’d appreciate it.

3 Answers

Most Helpful Answer

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Answered By Dr. Massimo Orioles, DVM, Cert AVP, MRCVS

Veterinarian

Published on November 24th, 2020

STeroids should be decreased gradually. After about 5 days of this treatment with 12 hours dose, you can decrease it to 5 every 24hours with food for 5 days then 5 mg every other day for other 5 times (10days) and then 2.5 mg every other day for 5 times. At the end of this you can stop it. I would recommend to stop methocarbamol gradually but after another check up at your local vet, so they can give you precise instructions on how to do it.

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Related Answers from Veterinarians

  • Published on June 9th, 2018

    The dose should be reduced gradually over the course of the following two weeks. If you give it once daily, start reducing it from full dose to half of it for 4-5 days and then progressively to half dose every other day for following 10 days and then stop it. If you give me more informations about dose and why was prescribed I can give you more specific specific advices about it. Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

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    Answered By Linda G, MS, DVM

    Veterinarian

    Published on July 23rd, 2019

    Hello. After 30 days on prednisone, I would take your time weaning your dog. Cut the dose by 50% every 2 weeks, so you can do 10 mg once a day for 2 weeks, then 5 mg once a day for 2 weeks finishing with 5 mg every other day for 2 weeks ( 7 doses ). Thanks for using Petco Pet Education Center, formerly Petcoach.

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