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Frontline didn't work for my dog. Can I reapply or switch flea meds?

Updated On September 23rd, 2025

Pet's info: Dog | Border Collie | Male | 10 years and 7 months old | 30 lbs

Dog had frontline plus 10 days ago. Hasn't worked. Can I reapply.

2 Answers

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on August 5th, 2020

Hi there. If Frontline is not working for your dog (which is sadly very common, in my experience), I would recommend using a different medication rather than reapplying a second dose. I normally recommend Nexgard, Bravecto, Simparica, or Credelio for fleas and ticks - all of these medications are safe and effective, and would be fine to give even if you applied Frontline 10 days ago.

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22Pet Parents found this answer helpful

Other Answers

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on October 13th, 2020

    Hi there. In my experience, Frontline Plus is not effective at all for fleas and has not been for several years now. So rather than applying another dose of the same med, I would recommend getting a prescription flea medication from your vet such as Nexgard or Bravecto - these meds are safe and very effective, and would be fine to give now even though he had Frontline last week since they are a completely different drug class.

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    3Pet Parents found this answer helpful

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