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Is sedating an old, aggressive dog with cancer for an exam risky?

Updated On September 23rd, 2025

Pet's info: Dog | Manchester Terrier (Standard) | Male | neutered | 16 years and 5 months old | 27 lbs

Is it risky to sedate a dog for an exam at age 16.5? he has melanoma cancer and now secondary skin infection but cannot he examined without being sedated (twilight) because of aggression. I don’t know if I should put him through that if his expectancy is short as it is. He’s 27lbs, Manchester terrier mix. Cancer has spread to lymph nodes...

2 Answers

Most Helpful Answer

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Answered By Lauren Jones VMD

Veterinarian

Published on July 3rd, 2020

Yes, there are certainly risks associated with sedating Rex. While age isn't a disease in and of itself, you mentioned that Rex has previously been diagnosed with metastatic (spread of cancer) melanoma. Existing disease processes raise the risk of sedation, which can include heart and blood pressure issues, or difficulty breaking down the drugs in the liver and/or kidneys. That said, I'd recommend having a conversation with Rex's vet regarding their previous exam findings, as well as the severity of his current skin infection. You'll need to weigh the risks and benefits of sedation vs. leaving this skin infection untreated. Your vet may recommend trying some different oral sedatives or anti-anxiety medications, which are often a bit safer than some injectable sedatives. Your vet may also be able to offer a telemedicine visit to check out Rex's skin. I hope that everything goes well!

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    Answered By Linda G, MS, DVM

    Veterinarian

    Published on

    Hello. This is always a difficult decision, but you have to assess the risk vs. benefits of sedation. Could a course of antibiotics be tried prior to proceeding, or is this just a wellness check to see how he is doing? At this age, I would be more inclined to see what can be done without sedation or causing him more stress. Unless there is vital information that needs to be gained only after sedation ( blood work?), I would opt to do as little sedation as possible. Good luck & thanks for contacting Petco Pet Education Center, formerly Petcoach.

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